The Familial Hypercholesterolemia Panel examines 5 genes associated with Familial Hypercholesterolemia (FH).
Who is this test for?
Patients with a personal and/or family history suggestive of a FH. Red flags for FH can include, but are not limited to, high cholesterol levels, very high levels of low-density lipoprotein, and cardiovascular disease.
What are the potential benefits for my patient?
Patients identified with FH can benefit from increased surveillance and preventative steps to better manage their risks. Medical intervention can include combination medication therapy, low-fat diet, exercise, weight control and not smoking. Also, your patient’s family members can be tested to help define their risk. If a pathogenic variant is identified in your patient, close relatives (children, siblings, parents) could have as high as a 50% risk to also be at increased risk. In some cases, screening should begin in childhood.