The Parkinson Disease Focus NGS Panel examines 7 genes associated with an increased risk of developing the neurodegenerative condition: Parkinson’s disease.
Who is this test for?
Patients with a personal and/or family history of Parkinson Disease. Parkinson Disease is characterized by progressive movement and balance issues. The progression of symptoms is often a bit different from one person to another due to the diversity of the disease. Warning signs include, but are not limited to involuntary shaking of the hands, legs, jaw or tongue (tremors), slow movement (bradykinesia), stiff limbs (rigidity), or gait (walking) and balance problems.
What are the potential benefits for my patient?
Patients identified with a disease-causing change (a pathogenic or likely pathogenic variant) in a gene on this panel have an increased risk of developing the associated neurodegenerative disease. Genetic testing may be beneficial in the planning and decision-making process for treatment, psychosocial counseling
, research study enrollment, and support programs for caregivers and patients. Your patient’s family members can also be tested to help define their risk. If a pathogenic variant is identified in your patient, close relatives (children, siblings, and parents) are up to 50% more likely to also be at increased risk.