Overview:

Fulgent's Pharmacogenetic (PGx) tests gives clinicians the tools to better understand how their patients will respond to certain medications.
With PGx testing, it’s possible to tailor medication plans to a patient’s specific genetic makeup. This can lead to reduced medical costs for patients and providers, safer medication plans, and more efficient drug efficacy. The PGx Comprehensive Panel includes genes associated with drug metabolism with high level evidence and clinically actionable guidelines, in addition to genes with PharmGKB evidence of 2 or higher.

What can testing tell us?

PGx testing can reveal if a person is a fast, normal, or slow metabolizer. A person’s metabolism changes the way their body responds to medication, including:
• Toxicity
Excessive amounts of the drug accumulate in the bloodstream, resulting in ADRs.

• Lack of Efficacy
The bloodstream cannot absorb enough of the drug to achieve a therapeutic effect.

• Hypersensitivity
Normal amounts of the drug enter the bloodstream, but even this is enough to trigger severe reactions in people with hypersensitivity to the medication.

What are the potential benefits for my patient?

Identify which drug may be most effective before treatment starts
PGx testing can help clinicians choose the most effective drug for each patient, minimize the risk of adverse reactions, and reduce hospitalizations.

Reduce the risk of adverse events related to certain drugs
PGx testing can assess a patient’s risk for adverse drug reactions before they take the medication which can improve patient safety and minimize costs for healthcare facilities.

Adjust and optimize the dose of current medications
PGx testing can help clinicians predict the appropriate dose of medication for their patient. This allows them to create more personalized medication plans to maximize efficacy and
reduce pharmacy costs.

Improved Patient Care
PGx test results become part of a patient’s medical record, allowing physicians to make more informed decisions when prescribing medications for future medical issues.